Research

Assess dynamic immune activity on any live tissue

Tumor biology is complex. Most models oversimplify biology and lose important context. elive™ is a first‑in‑class functional assay that preserves biology and makes it measurable. By capturing dynamic cytokine activity ex vivo, elive overcomes the limitations of static testing and provides a more accurate prediction of therapeutic responsiveness.

elive reveals immune activity in response to therapies enabling a stronger correlation with and translation to a clinical setting.

  • Basic researchers benefit from mechanistic immune-tumor insight in preserved human architecture.

  • Translational teams benefit from functional response data anchored in human biology.

  • Early drug developers get earlier, more confident go/no-go decisions.  


Innovations to support cytokine profiling of live tissue

elive_edge_horizontal_logo_rev

Proprietary automated cutting instrument

Ensures repeatability of testing: same tissue volume, same test article concentrations with small tissue volume
 
elive_gel_horizontal_logo_rev

Novel hydrogel to maintain biology

Preserves native architecture and immune infiltrates allowing for functional assessment

elive_method_horizontal_logo_rev

Control and treatment in a single well

A novel strategy to address tissue scarcity and mitigate heterogeneity in live tumor fragments 


Built for the entire research spectrum

elive preserves biology and makes it measurable, enabling functional human benchmarking.

The platform:

  • Uses live tissue
  • Standardizes tissue preparation
  • Relies on proprietary technology to preserve biological realsium
  • Uses a sequential treatment strategy to control heterogeneity

Ready to get into the details?

If you're interested in learning about how elive™ could accelerate scientific discovery, fill out the form below and we'll be in touch.

Pooja Advani
Pooja Advani,
MBBD, MD

Medical Oncologist
Breast Cancer
Mayo Clinic
David Braun
David Braun,
MD, PhD

Medical Oncologist
Kidney Cancer
Yale School of Medicine
Christian Capitini
Christian Capitini, MD
Director
UW Health | Carbone Cancer Center
Kevin Eliceiri
Kevin Eliceiri, PhD
Professor of Microscopy, Medical Imaging & AI
The University of Wisconsin-Madison
Janis_Marie_Taube
Janis Marie Taube,
MD, MSc

Pathologist
Melanoma
Johns Hopkins Medicine