We have developed an innovative platform that utilizes fresh tumor biopsies to preserve the tumor microenvironment for evaluating immunotherapy response. Using proprietary technology, we ensure optimal preservation and preparation of the biopsies. The process begins with Elephas Live Edge™, which precisely cuts the biopsy, followed by Elephas Live Protect™, a specialized hydrogel that encapsulates the live tissue. This ensures the integrity of the specimen before it undergoes assessment on the Elephas Live™ platform.
The tumor microenvironment includes various cell types in a distinct extracellular matrix. The interaction among tumor, noncancerous, and immune cells can create an immunosuppressive environment that promotes tumor progression. These complex interactions impact tumor formation, drug resistance, and immunotherapy response.
As we continued to advance the Elephas Live™ platform, we encountered a critical need: a hydrogel capable of encapsulating live tumor fragments (LTFs)™ while maintaining viability and original architecture. Existing options were inadequate; some were incompatible with our imaging instruments, while others, as biological products, were not reliable for reproducibility. To address this, we developed Elephas Live Protect™, a groundbreaking hydrogel designed specifically to meet the stringent requirements of live tissue analysis.
Read the latest data behind our platform.
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