Core needle biopsies present a unique challenge for live tissue analysis due to their small size and the high degree of heterogeneity both within and between specimens, even from the same tumor. Recognizing this limitation, the Elephas team leveraged the platform's ability to keep tissue alive to develop a novel method: each well in a well-plate functions as its own control and treatment arm. This innovative approach ensures robust and reliable detection of ex vivo responses to therapy, overcoming a significant barrier that has hindered similar systems in the past.
