Clinical Trials

Our Clinical Trials

We are conducting three observational clinical trials. The primary objective of these studies is to determine the ex-vivo predictive accuracy of elive™ across a variety of solid tumors.

Study endpoints:

  • Sensitivity and specificity of Elephas platform for predicting clinical response to immune checkpoint inhibitors
  • Compare to existing FDA approved biomarkers (PD-L1, MSI, MMR and TMB)
  • Compare between predicted responders and non-responders (ORR, DCR, PFS, OS)

Measured per RECIST v1.1 and iRECIST

Proud to be working with

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ELEPHAS-01: Lung Trial

Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform

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Tumor types:

Non-small cell lung cancer

Setting:

Metastatic & recurrent

Complete study details and locations: NCT05478538

ELEPHAS-02: Basket Trial

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

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Tumor types:

Bladder cancerColorectal cancerEndometrial cancerHead & neck cancerKidney cancerLiver cancerMelanomaNon-small cell lung cancer

Setting:

Metastatic & recurrentAdvanced

Complete study details and locations: NCT05520099

ELEPHAS-04: Mayo Clinic

Mayo Clinic MC230901: Observational Basket Trial to Collect Tissue to Develop and Train and Validate a Live Tumor Diagnostic Platform

Read the press release »

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Tumor types:

Bladder cancerColorectal cancerEndometrial cancerHead & neck cancerKidney cancerLiver cancerMelanomaNon-small cell lung cancerTriple negative breast cancerEsophageal cancerCervical cancer

Setting:

Metastatic & recurrentAdvancedNeoadjuvantAdjuvant

Complete study details: NCT06349642

These trials will provide an opportunity to demonstrate correlation between ex vivo and clinical response to immunotherapy regimens.

Clinical Trial Design

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We are enrolling over 600 patients in our studies.

Hospitals and academic research centers within the US provide consented patient specimens.

If you are a physician or researcher, contact us to learn more.

Contact Us